Rapid assembly of α-ketoamides through a decarboxylative strategy of isocyanates with α-oxocarboxylic acids under mild conditions
Author:
Affiliation:
1. School of Biotechnology and Health Sciences
2. Wuyi University
3. Jiangmen
4. China
5. Guangdong Provincial Key Laboratory of New Drug Screening
6. School of Pharmaceutical Sciences
7. Southern Medical University
8. Guangzhou 510515
Abstract
A simple and practical method for α-ketoamide synthesis via a decarboxylative strategy of isocyanates with α-oxocarboxylic acids at room temperature under metal- and solvent-free conditions is described.
Funder
Department of Education of Guangdong Province
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB00562F
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