Enantioselective [2 + 2] cycloaddition of 1,2-dihydroquinolines with 3-olefinic oxindoles <i>via</i> Brønsted acid catalysis-Reference-Cited by-同舟云学术

Enantioselective [2 + 2] cycloaddition of 1,2-dihydroquinolines with 3-olefinic oxindoles via Brønsted acid catalysis

Published:2022 Issue:6 Volume:9 Page:1621-1627
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Wang Biao¹,Yan Xiao²,Zhong Han¹,Ouyang Qin²^ORCID,Tian Xu¹^ORCID

Affiliation:

1. Key Laboratory of Molecular Target & Clinical Pharmacology and the State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences & the Fifth Affiliated Hospital, Guangzhou Medical University, Xinzao, Panyu District, Guangzhou, 511436, China

2. College of Pharmacy, Third Military Medical University, Chongqing, 400038, China

Abstract

A highly diastereo- and enantioselective Brønsted acid-catalyzed [2 + 2] cycloaddition generating heterocyclic products with four contiguous stereocenters in good to excellent yields with high stereoselectivities is reported.

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China

Guangdong Provincial Pearl River Talents Program

Guangzhou Municipal Science and Technology Project

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/QO/D1QO01708J

Reference66 articles.