Strengths and limitations of size exclusion chromatography for investigating single chain folding – current status and future perspectives

Author:

Engelke Johanna12345ORCID,Brandt Josef1234,Barner-Kowollik Christopher678910ORCID,Lederer Albena12345ORCID

Affiliation:

1. Polymer Separation Group

2. Leibniz-Institut für Polymerforschung Dresden e.V.

3. 01069 Dresden

4. Germany

5. Technische Universität Dresden

6. School of Chemistry

7. Physics and Mechanical Engineering

8. Queensland University of Technology (QUT)

9. Brisbane

10. Australia

Abstract

Synthetic approaches for Single-Chain Nanoparticles (SCNPs) developed rapidly during the last decade, opening a multitude of avenues for the design of functional macromolecular chains able to collapse into defined nanoparticles. However, the analytical evaluation of the SCNP formation process still requires critical improvements.

Funder

Australian Research Council

Queensland University of Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Polymers and Plastics,Biochemistry,Bioengineering

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