Incorporation of cisplatin into the metal–organic frameworks UiO66-NH2 and UiO66 – encapsulation vs. conjugation
Author:
Affiliation:
1. School of Chemistry
2. University of St Andrews
3. UK
4. UCL School of Pharmacy
5. University College London
6. London
7. School of Human Sciences
8. London Metropolitan University
Abstract
This work demonstrates synthetic strategies for the incorporation of an anticancer drug, cisplatin, and a Pt(iv) cisplatin prodrug into two zirconium-based metal–organic-frameworks (MOFs): UiO66 and UiO66-NH2.
Funder
British Heart Foundation
Engineering and Physical Sciences Research Council
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA14011K
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