Anticancer activity of pyrimidodiazepines based on 2-chloro-4-anilinoquinazoline: synthesis, DNA binding and molecular docking-Reference-Cited by-同舟云学术

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Anticancer activity of pyrimidodiazepines based on 2-chloro-4-anilinoquinazoline: synthesis, DNA binding and molecular docking

Published:2021 Issue:38 Volume:11 Page:23310-23329
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Cuartas Viviana¹²³⁴⁵^ORCID,Aragón-Muriel Alberto⁶⁷³⁸⁵,Liscano Yamil⁹¹⁰¹¹⁵,Polo-Cerón Dorian⁶⁷³⁸⁵,Crespo-Ortiz Maria del Pilar¹²¹³³¹⁴⁵,Quiroga Jairo¹²³⁴⁵,Abonia Rodrigo¹²³⁴⁵,Insuasty Braulio¹²³⁴⁵^ORCID

Affiliation:

1. Heterocyclic Compounds Research Group

2. Department of Chemistry

3. Universidad del Valle

4. A.A. 25360 Cali

5. Colombia

6. Laboratorio de Investigación en Catálisis y Procesos (LICAP)

7. Departamento de Química

8. Cali 760001

9. Grupo de Investigación en Química y Biotecnología (QUIBIO)

10. Universidad Santiago de Cali

11. Cali 760035

12. Grupo de Biotecnología e Infecciones Bacterianas

13. Departamento de Microbiología

14. Cali 760043

Abstract

A new series of quinazoline-based chalcones and pyrimidodiazepines were tested against 60 human tumor cell lines.

Funder

Universidad del Valle

Sistema General de Regalías de Colombia

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D1RA03509F

Reference65 articles.

1. Design and Synthesis of some new 2,4,6-trisubstituted quinazoline EGFR inhibitors as targeted anticancer agents

2. Antivascular and antitumor properties of the tubulin-binding chalcone TUB091

3. WHO, Cancer, https://www.who.int/health-topics/cancer#tab=tab_1

4. The Different Mechanisms of Cancer Drug Resistance: A Brief Review

5. Design and synthesis of a novel class EGFR/HER2 dual inhibitors containing tricyclic oxazine fused quinazolines scaffold

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1. Efficient synthesis and molecular docking analysis of quinazoline and azole hybrid derivatives as promising agents for anti-cancer and anti-tuberculosis activities;Journal of Molecular Structure;2024-08

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3. New pyridine‐based chalcones and pyrazolines with anticancer, antibacterial, and antiplasmodial activities;Archiv der Pharmazie;2024-03-28

4. Cytotoxic activity of quinolinequinones in cancer: In vitro studies, molecular docking, and ADME/PK profiling;Chemical Biology & Drug Design;2023-08-03

5. Targeting Colon Cancer Cells with Pyrazino‐Imidazolinone Derivatives: Synthesis, Molecular Docking, and in Vitro Evaluation of Anti‐Proliferative and Pro‐Apoptotic Activities;Chemistry & Biodiversity;2023-07-05

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