Lewisite exposure biomarkers in urine by liquid chromatography – inductively coupled plasma tandem mass spectrometry: with an accelerated matrix-matched stability study-Reference-Cited by-同舟云学术

Lewisite exposure biomarkers in urine by liquid chromatography – inductively coupled plasma tandem mass spectrometry: with an accelerated matrix-matched stability study

Published:2015 Issue:8 Volume:30 Page:1799-1808
ISSN:0267-9477
Container-title:Journal of Analytical Atomic Spectrometry
language:en
Short-container-title:J. Anal. At. Spectrom.

Author:

Palcic Jason D.¹²³⁴,Jones Janet S.¹²³⁴,Flagg E. Lindsay¹²³⁴,Donovan Stephen F.⁵⁶⁴

Affiliation:

1. Florida Department of Health

2. Bureau of Public Health Laboratories

3. Jacksonville

4. USA

5. NMS Labs

6. Willow Grove

Abstract

A simple and robust LC-ICP-MS/MS method is described for quantitative analysis of human urine for (2-chlorovinyl)arsonic acid (CVAOA), a metabolite of Lewisite.

Funder

Centers for Disease Control and Prevention

Publisher

Royal Society of Chemistry (RSC)

Subject

Spectroscopy,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/JA/C5JA00216H

Reference37 articles.

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2. Toxicity of vesicant agents scheduled for destruction by the Chemical Stockpile Disposal Program.

3. Chemical Warfare—A Chemical and Toxicological Review

4. Medical Management Guidelines for Blister Agents, Lewisite (L) (C2H2AsCl3) and Mustard-Lewisite Mixture (HL), http://www.atsdr.cdc.gov/MHMI/mmg163.pdf, accessed March, 2013

5. Pathological changes induced by lewisite and allied compounds

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