Extraction and untargeted analysis of metabolome from undemineralised cortical bone matrix

Author:

Bonicelli Andrea1,Taylor George2,Procopio Noemi1ORCID

Affiliation:

1. School of Law and Policing, Research Centre for Field Archaeology and Forensic Taphonomy, University of Central Lancashire, Preston, UK

2. Biological Mass Spectrometry (BioMS) Core Facility, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, M13 9PT, UK

Abstract

Single-phase bone metabolomic protocols for forensics are preferred to biphasic ones for repeatability and compound variety. Two combined chromatographic/mass spectrometry strategies maximise compound coverage from compromised skeletal remains.

Funder

UK Research and Innovation

Publisher

Royal Society of Chemistry (RSC)

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