Pre-targeting amyloid-β with antibodies for potential molecular imaging of Alzheimer's disease-Reference-Cited by-同舟云学术

Pre-targeting amyloid-β with antibodies for potential molecular imaging of Alzheimer's disease

Published:2023 Issue:16 Volume:59 Page:2243-2246
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Morgan Katherine A.¹^ORCID,de Veer Michael²^ORCID,Miles Luke A.³,Kelderman Cormac A. A.⁴^ORCID,McLean Catriona A.³,Masters Colin L.³,Barnham Kevin J.³,White Jonathan M.¹^ORCID,Paterson Brett M.²⁴^ORCID,Donnelly Paul S.¹^ORCID

Affiliation:

1. School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Melbourne, Victoria, 3010, Australia

2. Monash Biomedical Imaging, Monash University, Clayton, Victoria 3800, Australia

3. The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Victoria, 3010, Australia

4. School of Chemistry, Monash University, Clayton, Victoria 3800, Australia

Abstract

Amyloid-β antibodies were modified to incorporate trans-cyclooctene functional groups. Radiolabeled copper-64 probes, which can cross the blood–brain barrier and contain a 1,2,4,5-tetrazine functional group, react with the modified antibodies.

Funder

Australian Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CC/D2CC06850H

Reference23 articles.

1. Alzheimer disease

2. Clinical diagnosis of Alzheimer's disease: recommendations of the International Working Group

3. NIA‐AA Research Framework: Toward a biological definition of Alzheimer's disease

4. A critical appraisal of amyloid-β-targeting therapies for Alzheimer disease

5. Biomarkers for neurodegenerative diseases

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