In vitro evaluation of the enantiomeric R- and S-1,1′-binaphthyl-2,2′-diaminodichlorido–Pt(ii) complexes in human Burkitt lymphoma cells: emphasis on cellular accumulation, cytotoxicity, DNA binding, and ability to induce apoptosis-Reference-Cited by-同舟云学术

In vitro evaluation of the enantiomeric R- and S-1,1′-binaphthyl-2,2′-diaminodichlorido–Pt(ii) complexes in human Burkitt lymphoma cells: emphasis on cellular accumulation, cytotoxicity, DNA binding, and ability to induce apoptosis

Published:2018 Issue:2 Volume:10 Page:323-336
ISSN:1756-5901
Container-title:Metallomics
language:en
Short-container-title:Metallomics

Author:

Sørensen Belinda H.¹²³⁴⁵,Werth Patrick⁶⁷⁸⁹¹⁰,Lambert Ian H.¹²³⁴⁵^ORCID,Bednarski Patrick J.⁶⁷⁸⁹¹⁰

Affiliation:

1. Department of Biology

2. Section of Cell Biology and Physiology

3. The August Krogh Building

4. University of Copenhagen

5. Universitetsparken 13

6. Department of Medicinal Chemistry

7. Institute of Pharmacy

8. University of Greifswald

9. Friedrich-Ludwig-Jahn-Str. 17

10. Greifswald

Abstract

The aim of this project is to gain insights into the uptake and cellular actions of the enantiomeric R- and S-1,1′-binaphthyl-2,2′-diaminodichlorido–Pt(ii) complexes.

Funder

European Cooperation in Science and Technology

Publisher

Oxford University Press (OUP)

Subject

Metals and Alloys,Biochemistry,Biomaterials,Biophysics,Chemistry (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2018/MT/C7MT00237H

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