Formal enantioselective synthesis of nhatrangin A
Author:
Affiliation:
1. Université de Lyon – Université Claude Bernard Lyon 1 – CNRS – INSA Lyon – CPE Lyon
2. Institut de Chimie et Biochimie Moléculaires et Supramoléculaires – UMR 5246
3. 69622 Villeurbanne Cedex
4. France
Abstract
A new and straightforward synthesis of the C1–C7 core fragment of nhatrangin A was achieved in 14 steps from achiral 3-hydroxybenzaldehyde, without the need of chiral reagents or enzymatic resolution to introduce the chiral centers.
Funder
Région Auvergne-Rhône-Alpes
Université Claude Bernard Lyon 1
Centre National de la Recherche Scientifique
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/OB/C9OB02639H
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