Azlactone-based heterobifunctional linkers with orthogonal clickable groups: efficient tools for bioconjugation with complete atom economy-Reference-Cited by-同舟云学术

Azlactone-based heterobifunctional linkers with orthogonal clickable groups: efficient tools for bioconjugation with complete atom economy

Published:2018 Issue:39 Volume:16 Page:7124-7128
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Ho Hien The¹²³^ORCID,Bénard Alexandre¹²³,Forcher Gwenaël¹²³,Le Bohec Maël¹²³,Montembault Véronique¹²³,Pascual Sagrario¹²³,Fontaine Laurent¹²³^ORCID

Affiliation:

1. Institut des Molécules et Matériaux du Mans (IMMM) UMR 6283 CNRS – Le Mans Université

2. 72085 Le Mans cedex 9

3. France

Abstract

New azlactone-based heterobifunctional linkers that proceed in orthogonal click-like reactions for chemical ligations in biologically relevant medium without releasing any byproduct.

Funder

Centre National de la Recherche Scientifique

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/OB/C8OB01807C

Reference49 articles.

1. G. T. Hermanson , Bioconjugate Techniques , Academic Press , Boston , 3rd edn, 2013

2. Smart hybrid materials by conjugation of responsive polymers to biomacromolecules

3. Molecular Scaffolds Using Multiple Orthogonal Conjugations: Applications in Chemical Biology and Drug Discovery

4. Click reactions in protein chemistry: from the preparation of semisynthetic enzymes to new click enzymes

5. Bioorthogonal labelling of biomolecules: new functional handles and ligation methods

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