Beyond enzymatic promiscuity: asymmetric induction by l-proline on lipase catalyzed synthesis of polyfunctionalized 4H-pyrans-Reference-Cited by-同舟云学术

Beyond enzymatic promiscuity: asymmetric induction by l-proline on lipase catalyzed synthesis of polyfunctionalized 4H-pyrans

Published:2015 Issue:62 Volume:5 Page:50597-50603
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Bora Pranjal P.¹²³⁴,Bihani Manisha¹²³⁴,Bez Ghanashyam¹²³⁴

Affiliation:

1. Department of Chemistry

2. North Eastern Hill University

3. Shillong-793022

4. India

Abstract

We report herein the synthesis of polysubstituted 4H-pyrans catalysed by PPL via a three-component reaction of aldehyde, malononitrile and acetyl acetone. Addition of l-proline co-operatively induced stereoselective induction in the formation of polysubstituted 4H-pyrans.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA08785F

Reference47 articles.

1. Heteroaromatization with 4-Hydroxycoumarin Part II: Synthesis of Some New Pyrano[2,3-d]pyrimidines, [1,2,4]triazolo[1,5-c]pyrimidines and Pyrimido[1,6-b]-[1,2,4]triazine Derivatives

2. Synthesis and antiviral activity of phosphonate derivatives of enantiomeric dihydro-2H-pyranyl nucleosides

3. Synthesis of Pyrazolo[4′,3′:5,6]pyrano[2,3-d]pyrimidine Derivatives for Antiviral Evaluation

4. Synthesis and Evaluation of Anticonvulsant and Antimicrobial Activities of 3-Hydroxy-6-methyl-2-substituted 4H-Pyran-4-one Derivatives

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