A novel method to detect mutation in DNA by utilizing exponential amplification reaction triggered by the CRISPR-Cas9 system

Author:

Song Jayeon1234,Kim Soohyun1234ORCID,Kim Hyo Yong1234,Hur Kyung Hoon1234,Kim Yoosik1234,Park Hyun Gyu1234ORCID

Affiliation:

1. Department of Chemical and Biomolecular Engineering (BK 21+ program)

2. KAIST

3. Daejeon 34141

4. Republic of Korea

Abstract

We, herein, describe a novel method to detect mutation in DNA by utilizing exponential amplification reaction (EXPAR) triggered by clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9, called CRISPR–EXPAR.

Funder

Ministry of Science and ICT, South Korea

Ministry of Science, ICT and Future Planning

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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