NHPI-catalyzed electrochemical C–H alkylation of indoles with alcohols to access di(indolyl)methanes <i>via</i> radical coupling-Reference-Cited by-同舟云学术

NHPI-catalyzed electrochemical C–H alkylation of indoles with alcohols to access di(indolyl)methanes via radical coupling

Published:2022 Issue:24 Volume:9 Page:6861-6868
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Li Bingwen¹,Qin Hongyun²,Yan Kelu²^ORCID,Ma Jing²,Yang Jianjing²,Wen Jiangwei²^ORCID

Affiliation:

1. Shandong Key Laboratory of Biophysics, Institute of Biophysics, Dezhou University, Dezhou 253023, China

2. Key Laboratory of Green Natural Products and Pharmaceutical Intermediates in Colleges and Universities of Shandong Province, School of Chemistry and Chemical Engineering, Qufu Normal University, Qufu, 273165, China

Abstract

The present indirect electrochemically mediated radical protocol outperforms the traditional Friedel–Crafts route with a broad substrate scope and functional group tolerance, as well as facile gram-scale synthesis without metal contamination.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Shandong Province

Qufu Normal University

Dezhou University

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/QO/D2QO01498J

Reference62 articles.