A simple method for the synthesis of N-difluoromethylated pyridines and 4-pyridones/quinolones by using BrCF2COOEt as the difluoromethylation reagent-Reference-Cited by-同舟云学术

A simple method for the synthesis of N-difluoromethylated pyridines and 4-pyridones/quinolones by using BrCF2COOEt as the difluoromethylation reagent

Published:2020 Issue:50 Volume:10 Page:29829-29834
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Gandioso Albert¹²³⁴⁵,El Fakiri Mohamed¹²³⁴⁵,Rovira Anna¹²³⁴⁵,Marchán Vicente¹²³⁴⁵^ORCID

Affiliation:

1. Departament de Química Inorgànica i Orgànica, Secció de Química Orgànica

2. IBUB

3. Universitat de Barcelona

4. Barcelona

5. Spain

Abstract

A simple transition-metal free method was developed for the synthesis of N-difluoromethylated pyridinium-containing compounds and 4-pyridones/quinolones.

Funder

Departament d'Innovació, Universitats i Empresa, Generalitat de Catalunya

Secretaría de Estado de Investigación, Desarrollo e Innovación

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/RA/D0RA06322C

Reference41 articles.

1. Introduction of Fluorine and Fluorine-Containing Functional Groups

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3. Late-stage [18F]fluorination: new solutions to old problems

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