Rapid differentiation between bacterial infections and cancer using a near-infrared fluorogenic probe-Reference-Cited by-同舟云学术

Rapid differentiation between bacterial infections and cancer using a near-infrared fluorogenic probe

Published:2020 Issue:12 Volume:11 Page:3141-3145
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Wu Ling-Ling¹²³⁴⁵^ORCID,Wang Qinghua¹²³⁴⁵,Wang Yali¹²³⁴⁵,Zhang Na¹²³⁴⁵,Zhang Qingyang¹²³⁴⁵^ORCID,Hu Hai-Yu¹²³⁴⁵^ORCID

Affiliation:

1. State Key Laboratory of Bioactive Substances and Function of Natural Medicine

2. Beijing Key Laboratory of Active Substances Discovery and Drugability Evaluation

3. Institute of Materia Medica

4. Chinese Academy of Medical Sciences

5. Peking Union Medical College

Abstract

A new nitroreductase-responsive near-infrared fluorogenic probe can specifically image live bacteria in mouse models and does not accumulate at sites of inflammation or tumor.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/SC/D0SC00508H

Reference23 articles.

1. Optical Molecular Imaging of Inflammatory Cells in Interventional Medicine–An Emerging Strategy

2. Targeted imaging of bacterial infections: advances, hurdles and hopes

3. 42936 pathogens from Canadian hospitals: 10 years of results (2007–16) from the CANWARD surveillance study

4. An update on radiotracer development for molecular imaging of bacterial infections

5. Preclinical studies and prospective clinical applications for bacteria-targeted imaging: the future is bright

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