Small interfering RNA delivery by polyethylenimine-functionalised porous silicon nanoparticles-Reference-Cited by-同舟云学术

Small interfering RNA delivery by polyethylenimine-functionalised porous silicon nanoparticles

Published:2015 Issue:12 Volume:3 Page:1555-1565
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Hasanzadeh Kafshgari M.¹²³⁴⁵,Alnakhli M.⁶⁷⁸⁵,Delalat B.¹²³⁴⁵,Apostolou S.⁶⁷⁸⁵,Harding F. J.¹²³⁴⁵,Mäkilä E.⁹¹⁰¹¹¹²,Salonen J. J.⁹¹⁰¹¹¹²,Kuss B. J.⁶⁷⁸⁵,Voelcker N. H.¹²³⁴⁵

Affiliation:

1. ARC Centre of Excellence in Convergent Bio-Nano Science and Technology

2. Mawson Institute

3. University of South Australia

4. Adelaide SA 5001

5. Australia

6. School of Medicine

7. Flinders University

8. Adelaide

9. Department of Physics and Astronomy

10. University of Turku

11. FI-20014 Turku

12. Finland

Abstract

Polyethyleneimine-coated mesoporous silicon nanoparticles efficiently deliver siRNA in glioblastoma cells, subsequently reducing the protein expression of a chemotherapy resistance gene by 70% within 72 hours.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2015/BM/C5BM00204D

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