Thermal stability of G-rich anti-parallel DNA triplexes upon insertion of LNA and α-l-LNA-Reference-Cited by-同舟云学术

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Thermal stability of G-rich anti-parallel DNA triplexes upon insertion of LNA and α-l-LNA

Published:2015 Issue:18 Volume:13 Page:5115-5121
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Kosbar Tamer R.¹²³⁴⁵,Sofan Mamdouh A.⁶⁷⁸⁹¹⁰,Abou-Zeid Laila¹¹¹²¹³¹⁴¹⁰,Pedersen Erik B.¹²³⁴⁵

Affiliation:

1. Nucleic Acid Center

2. Department of Physics

3. Chemistry

4. and Pharmacy

5. University of Southern Denmark

6. Department of Chemistry

7. Faculty of Science

8. Damietta University

9. 34517 New Damietta

10. Egypt

11. Department of Pharmaceutical Organic Chemistry

12. Faculty of Pharmacy

13. Mansoura University

14. 35516 Mansoura

Abstract

G-rich anti-parallel DNA triplexes were modified with LNA or α-l-LNA in their Watson–Crick and TFO strands.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/OB/C5OB00535C

Reference41 articles.

1. A Proposed Structure For The Nucleic Acids

2. FORMATION OF A THREE-STRANDED POLYNUCLEOTIDE MOLECULE

3. V. N. Soyfer and V. N.Potaman, Triple-Helical Nucleic Acids, Springer, New York, 1996

4. Triple helix formation and the antigene strategy for sequence-specific control of gene expression

5. The triple helix: 50 years later, the outcome

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1. Synthesis of Oligonucleotides Carrying Nucleic Acid Derivatives of Biomedical and Structural Interest;Enzymatic and Chemical Synthesis of Nucleic Acid Derivatives;2018-10-26

2. Modified RNA triplexes: Thermodynamics, structure and biological potential;Scientific Reports;2018-08-29

3. PARTICLE triplexes cluster in the tumor suppressor WWOX and may extend throughout the human genome;Scientific Reports;2017-08-02

4. Structure-Specific Ligand Recognition of Multistranded DNA Structures;Current Topics in Medicinal Chemistry;2016-11-20

5. Anti-parallel triplexes: Synthesis of 8-aza-7-deazaadenine nucleosides with a 3-aminopropynyl side-chain and its corresponding LNA analog;Bioorganic & Medicinal Chemistry;2015-05

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