Pd-catalyzed imine-directed one-pot access to polysubstituted pyrroles<i>via</i>tandem triple isocyanide insertion/aza-Nazarov cyclization reactions-Reference-Cited by-同舟云学术

Pd-catalyzed imine-directed one-pot access to polysubstituted pyrrolesviatandem triple isocyanide insertion/aza-Nazarov cyclization reactions

Published:2023 Issue:13 Volume:10 Page:3252-3258
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Li Jun¹,Zhao Zhi-Wen¹,Zheng Shuang¹,He Ping¹,Qiu Ji-Ying¹,Zhou Quan-Quan²,Ren Zhi-Lin¹³^ORCID

Affiliation:

1. College of Chemical Engineering, Hubei University of Arts and Science, Xiangyang, 441053, Hubei, China

2. Institute of Advanced Materials (IAM), State-Province Joint Engineering Laboratory of Zeolite Membrane Materials, College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang, Jiangxi Province, 330022, P. R. China

3. Hubei Longzhong Laboratory, Xiangyang, 441000, Hubei, China

Abstract

A novel one-pot method for synthesizing polysubstituted pyrrole derivatives via three-component reactions of alkenyl bromides, amines, and isocyanides is reported by Pd catalysis, without additional ligands, with the orderly insertion of three isocyanide molecules.

Funder

Hubei University of Arts and Science

China Three Gorges University

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/QO/D3QO00598D

Reference62 articles.

1. Design, Synthesis and Investigation of New Diphenyl Substituted Pyridazinone Derivatives as Both Cholinesterase and Aβ-Aggregation Inhibitors