Direct electrochemical difluorination and azo-fluorination of <i>gem</i>-difluorostyrenes-Reference-Cited by-同舟云学术

Direct electrochemical difluorination and azo-fluorination of gem-difluorostyrenes

Published:2024 Issue:1 Volume:11 Page:142-148
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Wen Linzi¹²,Li Boao²,Zou Ziyan²,Zhou Naifu²,Sun Chengbo²,Feng Pengju²^ORCID,Li Hongsheng¹

Affiliation:

1. PET Center, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China

2. Department of Chemistry, Guangdong Provincial Key Laboratory of Functional Supramolecular Coordination Materials and Applications, Jinan University, Guangzhou, 510632, China

Abstract

A direct electrolysis protocol for difluorination and azo-fluorination of gem-difluorostyrenes was achieved involving Et3N·3HF as fluorine source. The electrochemical reduction of the benzyl C–F bond was also achieved.

Funder

Basic and Applied Basic Research Foundation of Guangdong Province

Jinan University

Shaanxi Normal University

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2024/QO/D3QO00599B

Reference67 articles.

1. Fluorine in Pharmaceuticals: Looking Beyond Intuition