Tailoring the positive and negative solvatochromism for chalcone analogues to detect heterozygous protein co-aggregation-Reference-Cited by-同舟云学术

Tailoring the positive and negative solvatochromism for chalcone analogues to detect heterozygous protein co-aggregation

Published:2023 Issue:27 Volume:59 Page:4016-4019
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Yulong Bai¹²³,Wang Wan¹,Yanan Huang³⁴,Jichun Wu³⁴,Lihua Liu³⁴,Biao Jing¹⁵,Junlin Chen³⁴,Xin Zhang³⁴^ORCID,Yu Liu¹^ORCID

Affiliation:

1. CAS Key Laboratory of Separation Science for Analytical Chemistry Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023, China

2. University of Chinese Academy of Sciences, Beijing 100049, China

3. Department of Chemistry, School of Science and Research Center for Industries of the Future, Westlake University, 600 Dunyu Road, Hangzhou 310030, Zhejiang Province, China

4. Westlake Laboratory of Life Sciences and Biomedicine, 18 Shilongshan Road, Hangzhou 310024, Zhejiang Province, China

5. The Second Hospital of Dalian Medical University, Dalian, China

Abstract

Modulating solvatochromism and anti-solvatochromism in a single fluorophore scaffold was achieved and these probes were utilized in visualizing biochemical processes.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CC/D3CC00545C

Reference25 articles.

1. Protein aggregation in amyotrophic lateral sclerosis

2. Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

3. D90A heterozygosity in the SOD1 gene is associated with familial and apparently sporadic amyotrophic lateral sclerosis

4. Macro-/micro-environment-sensitive chemosensing and biological imaging

5. Illuminating Protein Phase Separation: Reviewing Aggregation‐Induced Emission, Fluorescent Molecular Rotor and Solvatochromic Fluorophore Based Probes

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