LDL-mimetic lipid nanoparticles prepared by surface KAT ligation forin vivoMRI of atherosclerosis-Reference-Cited by-同舟云学术

LDL-mimetic lipid nanoparticles prepared by surface KAT ligation forin vivoMRI of atherosclerosis

Published:2020 Issue:44 Volume:11 Page:11998-12008
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Fracassi Alessandro¹²³⁴^ORCID,Cao Jianbo⁵⁶⁷⁸⁹^ORCID,Yoshizawa-Sugata Naoko¹⁰¹¹¹²¹³^ORCID,Tóth Éva¹⁴¹⁵¹⁶¹⁷¹⁸^ORCID,Archer Corey¹⁹²²⁰⁴^ORCID,Gröninger Olivier²¹²²²³⁴,Ricciotti Emanuela²⁴⁷⁸⁹,Tang Soon Yew²⁴⁷⁸⁹,Handschin Stephan²⁵²²⁶⁴,Bourgeois Jean-Pascal²⁷²⁸⁴,Ray Ankita¹²³⁴^ORCID,Liosi Korinne¹²³⁴^ORCID,Oriana Sean¹²³⁴,Stark Wendelin²¹²²²³⁴^ORCID,Masai Hisao¹⁰¹¹¹²¹³,Zhou Rong⁵⁶⁷⁸⁹^ORCID,Yamakoshi Yoko¹²³⁴^ORCID

Affiliation:

1. Laboratorium für Organische Chemie

2. ETH Zürich

3. CH-8093 Zürich

4. Switzerland

5. Department of Radiology

6. Institute for Translational Medicine and Therapeutics

7. University of Pennsylvania

8. Philadelphia

9. USA

10. Department of Genome Medicine

11. Tokyo Metropolitan Institute of Medical Science

12. Tokyo 156-8506

13. Japan

14. Centre de Biophysique Moléculaire

15. CNRS UPR 4301

16. Université dOrléans

17. Cedex 2

18. France

19. Institut für Geochemie und Petrologie

20. CH-8092 Zürich

21. Institute for Chemical and Bioengineering

22. ETH Zurich

23. CH-8093 Zurich

24. Department of Systems Pharmacology and Translational Therapeutics

25. Scientific Center for Optical and Electron Microscopy

26. Zürich

27. University of Applied Science and Arts Western Switzerland

28. CH-1700 Fribourg

Abstract

LDL-mimetic lipid nanoparticles, decorated with MRI contrast agents and fluorescent dyes, were prepared by the covalent attachments of an apoB100-mimetic peptide, Gd(iii)-chelate, and rhodamine to enhance atherosclerosis in thein vivoimaging.

Funder

American Heart Association

Japan Society for the Promotion of Science

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Eidgenössische Technische Hochschule Zürich

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/SC/D0SC04106H

Reference48 articles.