A novel lysosome-targeted fluorogenic probe based on 5-triazole-quinoline for the rapid detection of hydrogen sulfide in living cells-Reference-Cited by-同舟云学术

A novel lysosome-targeted fluorogenic probe based on 5-triazole-quinoline for the rapid detection of hydrogen sulfide in living cells

Published:2018 Issue:5 Volume:16 Page:712-716
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Dou Yandong¹²³⁴⁵,Gu Xiaoxu⁵²³⁴,Ying Shasha⁵²³⁴,Zhu Shen⁵²³⁴,Yu Shian⁶⁷⁸⁴,Shen Wei⁶⁷⁸⁴,Zhu Qing¹²³⁴⁵^ORCID

Affiliation:

1. Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals

2. Zhejiang University of Technology

3. Hangzhou 310014

4. China

5. College of Biotechnology and Bioengineering

6. Department of General Surgery

7. Jinhua Central Hospital

8. Jinhua 321000

Abstract

A fluorogenic probe based on the novel fluorophore 5-triazole-quinoline was developed for the detection of hydrogen sulfide, an endogenous signaling molecule associated with the development of various diseases.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/OB/C7OB02881D

Reference35 articles.

1. Chemiluminescent Detection of Enzymatically Produced Hydrogen Sulfide: Substrate Hydrogen Bonding Influences Selectivity for H2S over Biological Thiols

2. Understanding Hydrogen Sulfide Storage: Probing Conditions for Sulfide Release from Hydrodisulfides

3. Factors Controlling the Reactivity of Hydrogen Sulfide with Hemeproteins

4. Relative Contributions of Cystathionine β-Synthase and γ-Cystathionase to H2S Biogenesis via Alternative Trans-sulfuration Reactions

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