Luteolin inhibits proliferation and induces apoptosis of human melanoma cells in vivo and in vitro by suppressing MMP-2 and MMP-9 through the PI3K/AKT pathway
Author:
Affiliation:
1. Department of Pharmacy
2. The First Affiliated Hospital of Soochow University
3. Suzhou
4. PR China
5. Department of Chinese medicine
6. Taizhou Institute for Food and Drug Control
7. Taizhou
8. Soochow University Affiliated Children's Hospital
Abstract
Since the incidence rate of malignant melanoma is increasing annually, development of drugs against melanoma cell metastasis has become more urgent.
Funder
Wu Jieping Medical Foundation
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
General Medicine,Food Science
Link
http://pubs.rsc.org/en/content/articlepdf/2019/FO/C8FO02013B
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5. Involvement of PI3K/PTEN/AKT/mTOR pathway in invasion and metastasis in hepatocellular carcinoma: Association with MMP-9
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