Luteolin inhibits proliferation and induces apoptosis of human melanoma cells in vivo and in vitro by suppressing MMP-2 and MMP-9 through the PI3K/AKT pathway-Reference-Cited by-同舟云学术

Luteolin inhibits proliferation and induces apoptosis of human melanoma cells in vivo and in vitro by suppressing MMP-2 and MMP-9 through the PI3K/AKT pathway

Published:2019 Issue:2 Volume:10 Page:703-712
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Yao Xin¹²³⁴,Jiang Wei⁵⁶⁷⁴,Yu Danhong¹⁸³⁴,Yan Zhaowei¹²³⁴^ORCID

Affiliation:

1. Department of Pharmacy

2. The First Affiliated Hospital of Soochow University

3. Suzhou

4. PR China

5. Department of Chinese medicine

6. Taizhou Institute for Food and Drug Control

7. Taizhou

8. Soochow University Affiliated Children's Hospital

Abstract

Since the incidence rate of malignant melanoma is increasing annually, development of drugs against melanoma cell metastasis has become more urgent.

Funder

Wu Jieping Medical Foundation

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2019/FO/C8FO02013B

Reference32 articles.

1. Progression of cutaneous melanoma: implications for treatment

2. Current and Future Trials of Targeted Therapies in Cutaneous Melanoma

3. Prognostic value of matrix metalloproteinases (MMP-2 and MMP-9) in patients with lymph node-negative breast carcinoma

4. New functions for the matrix metalloproteinases in cancer progression

5. Involvement of PI3K/PTEN/AKT/mTOR pathway in invasion and metastasis in hepatocellular carcinoma: Association with MMP-9

Cited by 95 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Flavonoid compounds and their synergistic effects: Promising approaches for the prevention and treatment of psoriasis with emphasis on keratinocytes – A systematic and mechanistic review;International Immunopharmacology;2024-09

2. Progress, pharmacokinetics and future perspectives of luteolin modulating signaling pathways to exert anticancer effects: A review;Medicine;2024-08-23

3. Exploring the Molecular Mechanisms of Herbs in the Treatment of Hyperlipidemia Based on Network Pharmacology and Molecular Docking;Journal of Medicinal Food;2024-08-16

4. Boosting immunity: synergistic antiviral effects of luteolin, vitamin C, magnesium and zinc against SARS-CoV-2 3CLpro;Bioscience Reports;2024-08

5. Unraveling the Anti-Obesity Potential of Luteolin: Mechanistic Insights;Current Nutrition & Food Science;2024-07-25