Bioorthogonal double-fluorogenic siliconrhodamine probes for intracellular super-resolution microscopy

Author:

Kozma E.12345,Estrada Girona G.678910ORCID,Paci G.678910ORCID,Lemke E. A.678910,Kele P.12345ORCID

Affiliation:

1. “Lendület” Chemical Biology Research Group

2. Institute of Organic Chemistry

3. Research Centre for Natural Sciences

4. Hungarian Academy of Sciences

5. 1117 Budapest

6. Structural and Computational Biology Unit

7. Cell Biology and Biophysics Unit

8. European Molecular Biology Laboratory

9. Heidelberg

10. Germany

Abstract

A series of double-fluorogenic siliconrhodamine-tetrazines were synthesized. One of these tetrazines is a membrane-permeant label allowing site-specific bioorthogonal tagging of intracellular proteins and super-resolution imaging.

Funder

Emberi Eroforrások Minisztériuma

Nemzeti Kutatási és Technológiai Hivatal

Magyar Tudományos Akadémia

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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