Water soluble Ru(ii)–arene complexes of the antidiabetic drug metformin: DNA and protein binding, molecular docking, cytotoxicity and apoptosis-inducing activity-Reference-Cited by-同舟云学术

Water soluble Ru(ii)–arene complexes of the antidiabetic drug metformin: DNA and protein binding, molecular docking, cytotoxicity and apoptosis-inducing activity

Published:2017 Issue:60 Volume:7 Page:37706-37719
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Gopalakrishnan Durairaj¹²³⁴,Ganeshpandian Mani¹²³⁴^ORCID,Loganathan Rangasamy¹⁵⁶⁷,Bhuvanesh Nattamai S. P.⁸¹⁹¹⁰⁷,Sabina Xavier Janet¹¹¹¹²⁴^ORCID,Karthikeyan J.¹¹¹¹²⁴

Affiliation:

1. Department of Chemistry

2. SRM University

3. Chennai – 603 203

4. India

5. Purdue University

6. West Lafayette

7. USA

8. X-ray Diffraction Lab

9. Texas A&M University

10. College Station

11. Sathyabama University

12. Chennai – 600119

Abstract

The incorporation of antidiabetic drug metformin with organometallic Ru(arene) pharmacophore is a promising approach to develop new anticancer agents.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/RA/C7RA06514K

Reference83 articles.

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