Physical mixture of a cyclic lipopeptide vaccine induced high titres of opsonic IgG antibodies against group A streptococcus-Reference-Cited by-同舟云学术

Physical mixture of a cyclic lipopeptide vaccine induced high titres of opsonic IgG antibodies against group A streptococcus

Published:2022 Issue:1 Volume:10 Page:281-293
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Madge Harrison Y. R.¹^ORCID,Huang Wenbin¹^ORCID,Gilmartin Lachlan¹,Rigau-Planella Berta¹,Hussein Waleed M.¹,Khalil Zeinab G.²,Koirala Prashamsa¹,Santiago Viviene S.²^ORCID,Capon Robert J.²^ORCID,Toth Istvan¹²³^ORCID,Stephenson Rachel J.¹^ORCID

Affiliation:

1. School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane 4072, Australia

2. Institute for Molecular Bioscience, The University of Queensland, St Lucia, Queensland 4072, Australia

3. School of Pharmacy, The University of Queensland, Brisbane 4072, Australia

Abstract

The presence of a cyclic peptide is as part of a physically-mixed group A Streptococcus vaccine for the induction of a strong, balanced Th1/Th2 immune response.

Funder

National Health and Medical Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2022/BM/D1BM01333E

Reference45 articles.

1. Peptide-Based Vaccines: Current Progress and Future Challenges

2. Emerging concepts in the science of vaccine adjuvants

3. Peptide-based synthetic vaccines