Injectable small molecule hydrogel as a potential nanocarrier for localized and sustained in vivo delivery of doxorubicin

Author:

Singh Manish123,Kundu Somanath12345,Reddy M Amarendar678,Sreekanth Vedagopuram12345,Motiani Rajender K.910,Sengupta Sagar1110,Srivastava Aasheesh678,Bajaj Avinash12345

Affiliation:

1. Laboratory of Nanotechnology and Chemical Biology

2. Regional Centre for Biotechnology

3. Gurgaon-122016, India

4. Manipal University

5. Manipal, India

6. Department of Chemistry

7. Indian Institute of Science Education and Research

8. Bhopal, India

9. Institute of Genomics and Integrative Biology

10. New Delhi, India

11. National Institute of Immunology

Abstract

We report l-alanine based small molecule injectable hydrogel that can entrap doxorubicin and show in vivo anticancer effect due to sustained release of the drug.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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