C(sp<sup>2</sup>)–H selenylation of substituted benzo[4,5]imidazo[2,1-<i>b</i>]thiazoles using phenyliodine(<scp>iii</scp>)bis(trifluoroacetate) as a mediator-Reference-Cited by-同舟云学术

C(sp²)–H selenylation of substituted benzo[4,5]imidazo[2,1-b]thiazoles using phenyliodine(iii)bis(trifluoroacetate) as a mediator

Published:2024 Issue:7 Volume:14 Page:4462-4470
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Ghosh Prasanjit¹^ORCID,Chhetri Gautam¹,Mandal Anirban¹,Chen Yu²³^ORCID,Hersh William H.²³,Das Sajal¹^ORCID

Affiliation:

1. Department of Chemistry, University of North Bengal, Darjeeling-734013, India

2. Department of Chemistry and Biochemistry, Queens College and the Graduate Centre of City University of New York, Flushing, New York 11367-1597, USA

3. PhD Program in Chemistry, The Graduate Center of the City University of New York, 365 Fifth Ave., New York, 10016, USA

Abstract

A metal-free regioselective C–H selenylation of substituted benzo[4,5]imidazo[2,1-b]thiazoles is devised to prepare structurally diverse selenoether derivatives in good to excellent yields. The reaction is scalable and follows radical pathways.

Funder

University Grants Commission

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RA/D4RA00057A

Reference48 articles.

1. Synthesis and Antibacterial Activity of a Novel Series of 2,3-Diaryl-substituted-imidazo(2,1-b)-benzothiazole Derivatives

2. Discovery of Imidazo[1,2-b]thiazole Derivatives as Novel SIRT1 Activators

3. Antitumor Activity of New Substituted 3-(5-Imidazo[2,1-b]thiazolylmethylene)-2-indolinones and 3-(5-Imidazo[2,1-b]thiadiazolylmethylene)-2-indolinones: Selectivity against Colon Tumor Cells and Effect on Cell Cycle-Related Events

4. New imidazo[2,1-b]thiazole derivatives: Synthesis, in vitro anticancer evaluation, and in silico studies

5. Small Molecule Inhibitor of Mitotic Spindle Bipolarity Identified in a Phenotype-Based Screen