CXCR4-antagonist Peptide R-liposomes for combined therapy against lung metastasis

Author:

Ieranò Caterina1234,Portella Luigi1234,Lusa Sara567,Salzano Giuseppina56789,D'Alterio Crescenzo1234,Napolitano Maria1234,Buoncervello Maria10111213,Macchia Daniele10111213,Spada Massimo10111213,Barbieri Antonio14234,Luciano Antonio14234,Barone Maria Vittoria1516177,Gabriele Lucia10111213,Caraglia Michele1819207,Arra Claudio14234,De Rosa Giuseppe567,Scala Stefania1234

Affiliation:

1. Molecular Immunology and Immune regulation

2. Istituto Nazionale per lo Studio e la Cura dei Tumori

3. Fondazione “G. Pascale”-IRCCS

4. Italy

5. Department of Pharmacy

6. University of Naples Federico II

7. Naples, Italy

8. Center for Pharmaceutical Biotechnology and Nanomedicine

9. Northeastern University

10. Department of Hematology

11. Oncology and Molecular Medicine

12. Istituto Superiore di Sanità

13. Rome, Italy

14. Animal Facility

15. Department of Translational Medical Science and European Laboratory for the Investigation of Food Induced Disease (ELFID)

16. University of Naples

17. Federico II

18. Department of Biochemistry

19. Biophysics and General Pathology

20. Second University of Naples

Abstract

PL-Peptide R potentiates the Peptide R efficacy and efficiently delivers doxorubicin in melanoma lung metastasis.

Funder

Associazione Italiana per la Ricerca sul Cancro

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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