Two- and three-photon excitable quaternized imidazo[1,2-a]pyridines as mitochondrial imaging and potent cancer therapy agents-Reference-Cited by-同舟云学术

Two- and three-photon excitable quaternized imidazo[1,2-a]pyridines as mitochondrial imaging and potent cancer therapy agents

Published:2020 Issue:38 Volume:18 Page:7571-7576
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Hase Eiji¹²³⁴⁵,Takanari Hiroki⁶³⁴⁵⁷,Hoshi Keita⁸³⁴⁵,Okamoto Masaki⁸³⁴⁵,Tabata Atsushi⁹³¹⁰⁵,Nagamune Hideaki⁹³¹⁰⁵,Minamikawa Takeo¹²³⁴⁵,Yasui Takeshi¹²³⁴⁵,Yoshida Yasushi¹¹¹²¹³¹⁴⁵,Minagawa Keiji⁸³⁴⁵,Kawamura Yasuhiko⁸³⁴⁵,Imada Yasushi⁸³⁴⁵^ORCID,Yagishita Fumitoshi¹²³⁴⁵^ORCID

Affiliation:

1. Department of Post-LED Photonics Research

2. Institute of Post-LED Photonics

3. Tokushima University

4. Tokushima 770-8506

5. Japan

6. Research Cluster on “Multi-scale Vibrational Microscopy for Comprehensive Diagnosis and Treatment of Cancer”

7. Department of Interdisciplinary Researches for Medicine and Photonics

8. Department of Applied Chemistry

9. Department of Bioscience and Bioindustry

10. Tokushima 770-8513

11. Department of Applied Chemistry and Biotechnology

12. Graduate School of Engineering

13. Chiba University

14. Chiba 263-8522

Abstract

We have synthesized four blue fluorescent imidazo[1,2-a]pyridines. One specific compound work as not only a two- and three-photon fluorescence imaging agent for the visualization of mitochondria, but also a potent mitochondria-targeted photodynamic therapy agent.

Funder

Japan Society for the Promotion of Science

University of Tokushima

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/OB/D0OB01585G

Reference36 articles.

1. Two-Photon Laser Scanning Fluorescence Microscopy

2. Multiphoton microscopy in life sciences