A colorimetric and ratiometric fluorescent probe for distinguishing cysteine from biothiols in water and living cells

Author:

Han Qingxin123,Shi Zhaohua123,Tang Xiaoliang123,Yang Lizi123,Mou Zuolin123,Li Jing423,Shi Jinmin123,Chen Chunyang123,Liu Wei123,Yang Huan123,Liu Weisheng123

Affiliation:

1. Key Laboratory of Nonferrous Metals Chemistry and Resources Utilization of Gansu Province and State Key Laboratory of Applied Organic Chemistry

2. Lanzhou University

3. Lanzhou 730000, P. R. China

4. College of Pharmacy

Abstract

A highly selective merocyanine-based fluorescent probe was developed, which can significantly distinguish Cys from Hcy and GSH by their kinetic profiles in water and respond to the intracellular Cys.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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