Practically convenient and industrially-aligned methods for iridium-catalysed hydrogen isotope exchange processes-Reference-Cited by-同舟云学术

Practically convenient and industrially-aligned methods for iridium-catalysed hydrogen isotope exchange processes

Published:2014 Issue:22 Volume:12 Page:3598-3603
ISSN:1477-0520
Container-title:Org. Biomol. Chem.
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Cochrane A. R.¹²³⁴,Idziak C.¹²³⁴,Kerr W. J.¹²³⁴,Mondal B.¹²³⁴,Paterson L. C.¹²³⁴,Tuttle T.¹²³⁴,Andersson S.⁵⁶⁷⁸,Nilsson G. N.⁵⁶⁷⁸

Affiliation:

1. Department of Pure and Applied Chemistry

2. WestCHEM

3. University of Strathclyde

4. Glasgow, UK

5. Medicinal Chemistry

6. AstraZeneca

7. R&D Mölndal

8. SE-431 83 Mölndal, Sweden

Abstract

The use of alternative solvents in the iridium-catalysed hydrogen isotope exchange reaction with developing phosphine/NHC Ir(i) complexes has identified reaction media which are more widely applicable than the commonly employed chlorinated solvent, dichloromethane.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/OB/C4OB00465E

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