Bromine-radical-induced Csp2–H difluoroalkylation of quinoxalinones and hydrazones through visible-light-promoted Csp3–Br bond homolysis-Reference-Cited by-同舟云学术

Bromine-radical-induced C_sp²–H difluoroalkylation of quinoxalinones and hydrazones through visible-light-promoted C_sp³–Br bond homolysis

Published:2022 Issue:15 Volume:9 Page:4135-4145
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Qu Chuan-Hua¹^ORCID,Huang Run¹,Liu Yuan¹,Liu Tong¹,Song Gui-Ting¹

Affiliation:

1. College of Pharmacy, National & Local Joint Engineering Research Center of Targeted and Innovative Therapeutics, Chongqing Key Laboratory of Kinase Modulators as Innovative Medicine, Chongqing University of Arts and Sciences, Chongqing 402160, China

Abstract

Bromine radicals derived from photo-induced Csp3–Br bond homolysis can mediate H abstraction/imine radical formation from quinoxalinones and hydrazones, which in turn quench the in situ-generated difluoroalkyl radicals to furnish the products.

Funder

National Natural Science Foundation of China

Chongqing Municipal Education Commission

Chongqing University of Arts and Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/QO/D2QO00710J

Reference115 articles.

1. Merging Photoredox with 1,2-Metallate Rearrangements: The Photochemical Alkylation of Vinyl Boronate Complexes