Analysis of endogenous metabolites using multifunctional derivatization and capillary RPLC-MS-Reference-Cited by-同舟云学术

Analysis of endogenous metabolites using multifunctional derivatization and capillary RPLC-MS

Published:2022 Issue:35 Volume:14 Page:3397-3404
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Agongo Julius¹,Armbruster Michael¹^ORCID,Arnatt Christopher¹,Edwards James¹^ORCID

Affiliation:

1. Department of Chemistry and Biochemistry, Saint Louis University, 3501 Laclede Ave, St Louis, MO, 63103, USA

Abstract

Multi-functional derivatization of metabolites increases retention, signal intensity, and reproducibility for expanded coverage. This system detects 32 metabolic perturbations in endothelial cells upon epinephrine treatment.

Funder

National Institute of General Medical Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/AY/D2AY01108E

Reference39 articles.

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4. Comparison of Targeted and Untargeted Approaches in Breath Analysis for the Discrimination of Lung Cancer from Benign Pulmonary Diseases and Healthy Persons

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