Modular synthesis of 3,3-disubstituted oxindoles from nitrones and acrylic acids-Reference-Cited by-同舟云学术

Modular synthesis of 3,3-disubstituted oxindoles from nitrones and acrylic acids

Published:2024 Issue:31 Volume:22 Page:6282-6287
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Suzuki Hirotsugu¹^ORCID,Sekino Kaisei²,Kondo Sora²,Minamikawa Ryo²,Matsuda Takanori²^ORCID

Affiliation:

1. Tenure-Track Program for Innovative Research, University of Fukui, 3-9-1 Bunkyo, Fukui-shi, Fukui 910-8507, Japan

2. Department of Applied Chemistry, Tokyo University of Science, 1-3 Kagurazaka, Shinjuku-ku, Tokyo 162-8601, Japan

Abstract

A novel modular synthetic method for 3,3-disubstituted oxindole has been developed, utilising easily preparable and stable nitrones and carboxylic acids.

Funder

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/OB/D4OB00964A

Reference71 articles.

1. Spirooxindoles: Promising scaffolds for anticancer agents

2. Oxindole: A chemical prism carrying plethora of therapeutic benefits

3. Oxindole and its derivatives: A review on recent progress in biological activities

4. Construction of Spiro[pyrrolidine‐3,3′‐oxindoles] − Recent Applications to the Synthesis of Oxindole Alkaloids

5. Catalytic Asymmetric Synthesis of Oxindoles Bearing a Tetrasubstituted Stereocenter at the C-3 Position

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