Solvatomorphism and first-time observation of acid–acid catemer in 4-phenylamino-benzoic acids

Author:

Liu Xiaoting1,Cui Jingliang1,Zeng Qun2,Fang Liwen2,Liang Peng-Yu3,Zhou Pan-Pan3ORCID,Parkin Sean4ORCID,Li Tonglei5ORCID,Ruan Shigang2,Long Sihui1ORCID

Affiliation:

1. Key Laboratory for Green Chemical Process of Ministry of Education, Hubei Key Laboratory of Novel Reactor and Green Chemical Technology, Hubei Engineering Research Center for Advanced Fine Chemicals, School of Chemical Engineering and Pharmacy, Wuhan Institute of Technology, 206 1st Rd Optics Valley, East Lake New Technology Development District, Wuhan, Hubei 430205, China

2. XtalPi Inc, The 3rd Floor of the Second Phase of the International Biomedical Industrial Park, No. 2 Hongliu Road, Futian District, Shenzhen 518000, China

3. College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, China

4. Department of Chemistry, University of Kentucky, Lexington, Kentucky 40506, USA

5. Department of Industrial and Physical Pharmacy, Purdue University, West Lafayette, Indiana 47907, USA

Abstract

A series of 4-phenylamino-benzoic acids (1–8) varying in the substitution position and pattern were synthesized, and their polymorphism was investigated. The rare acid–acid catemer motif was observed for the first time in the crystal structure of one of the compounds.

Funder

Natural Science Foundation of Hubei Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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