Copper-catalyzed asymmetric propargylic substitution with salicylaldehyde-derived imine esters

Author:

Wang Ruo-Qing12,Shen Chong1,Cheng Xiang1,Dong Xiu-Qin13ORCID,Wang Chun-Jiang12ORCID

Affiliation:

1. Engineering Research Center of Organosilicon Compounds & Materials, Ministry of Education, College of Chemistry and Molecular Sciences, Suzhou Institute of Wuhan University, Wuhan University, Wuhan, Hubei, 430072, P. R. China

2. State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Shanghai, 230021, China

3. Suzhou Institute of Wuhan University, Suzhou, Jiangsu, 215123, P. R. China

Abstract

Cu-catalyzed asymmetric propargylic substitution with salicylaldehyde-derived imine esters was successfully realized, generating a series of chiral amino acid derivatives containing propargylic groups with excellent results.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Hubei Province

Natural Science Foundation of Jiangsu Province

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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