Exploring apoptotic induction of malabaricone A in triple-negative breast cancer cells: an acylphenol phyto-entity isolated from the fruit rind of <i>Myristica malabarica</i> Lam.-Reference-Cited by-同舟云学术

Exploring apoptotic induction of malabaricone A in triple-negative breast cancer cells: an acylphenol phyto-entity isolated from the fruit rind of Myristica malabarica Lam.

Published:2024 Issue: Volume: Page:
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

Vimalkumar Pothiyil S.¹²^ORCID,Sivadas Neethu¹²,Murali Vishnu Priya¹^ORCID,Sherin Daisy R.³,Murali Madhukrishnan¹²,Joseph Anuja Gracy¹²,Radhakrishnan Kokkuvayil Vasu¹²^ORCID,Maiti Kaustabh Kumar¹²^ORCID

Affiliation:

1. Chemical Sciences and Technology Division, CSIR-National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Thiruvananthapuram-695019, India

2. Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India

3. School of Digital Sciences, Kerala University of Digital Sciences, Innovation and Technology, Digital University Kerala, Thiruvananthapuram-695317, India

Abstract

Malabaricone A isolated from Myristica malabarica induces apoptosis in triple-negative breast cancer cells through intrinsic and extrinsic pathways, which is validated through in vitro and in silico studies and resembles a potent phyto-entity.

Funder

Council of Scientific and Industrial Research, India

Indian Council of Medical Research

University Grants Commission

Department of Health Research, India

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/MD/D4MD00391H

Reference73 articles.

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