Diels–Alder crosslinked HA/PEG hydrogels with high elasticity and fatigue resistance for cell encapsulation and articular cartilage tissue repair-Reference-Cited by-同舟云学术

Diels–Alder crosslinked HA/PEG hydrogels with high elasticity and fatigue resistance for cell encapsulation and articular cartilage tissue repair

Published:2014 Issue:17 Volume:5 Page:5116-5123
ISSN:1759-9954
Container-title:Polym. Chem.
language:en
Short-container-title:Polym. Chem.

Author:

Yu Feng¹²³⁴³,Cao Xiaodong¹²³⁴³,Li Yuli¹²³⁵²,Zeng Lei¹²³⁵²,Zhu Jiehua¹²³⁴³,Wang Gang¹²³⁵²,Chen Xiaofeng¹²³⁴³

Affiliation:

1. School of Materials Science and Engendering

2. South China University of Technology

3. Guangzhou, PR China

4. National Engineering Research Centre for Tissue Restoration and Reconstruction

5. Guangdong Province Key Laboratory of Biomedical Engineering

Abstract

The gelation time of Diels–Alder crosslinked HA/PEG hydrogels can be reduced to an appropriate level for cell encapsulation and survival. At the same time, the DA click reaction makes the gel highly resilient and resistant to cyclic compression loading, which biomimics native articular cartilage biomechanical functions.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Polymers and Plastics,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2014/PY/C4PY00473F

Reference54 articles.

1. Articular cartilage: structure, injuries and review of management

2. Articular Cartilage: Injuries and Potential for Healing

3. Articular Cartilage Injuries

4. Injectable cartilage tissue engineering

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