Easy access to Ugi-derived isatin-peptoids and their potential as small-molecule anticancer agents-Reference-Cited by-同舟云学术

Easy access to Ugi-derived isatin-peptoids and their potential as small-molecule anticancer agents

Published:2023 Issue:2 Volume:47 Page:743-750
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Marques Carolina S.¹^ORCID,González-Bakker Aday²^ORCID,Padrón José M.²^ORCID,Burke Anthony J.¹³⁴^ORCID

Affiliation:

1. LAQV-REQUIMTE, University of Évora, Institute for Research and Advanced Studies, Rua Romão Ramalho, 59, 7000-641, Évora, Portugal

2. BioLab, Instituto Universitario de Bio-Orgánica Antonio González (IUBO-AG) Universidad de La Laguna, PO Box 456, 38200, La Laguna, Spain

3. Faculty of Pharmacy, University of Coimbra, Pólo das Ciências da Saúde, Azinhaga de Santa Comba, 3000-548, Coimbra, Portugal

4. Centro de Química de Coimbra, Institute of Molecular Sciences, Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade de Coimbra, 3004-535, Coimbra, Portugal

Abstract

A remarkable Ugi4CR approach to access a library of isatin-based α-acetoamide carboxamide oxindole derivatives with promising antiproliferative activity.

Funder

Consejería de Educación, Universidades, Cultura y Deportes, Gobierno de Canarias

Fundação para a Ciência e a Tecnologia

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/NJ/D2NJ03627D

Reference50 articles.

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2. M.Kaur , Chapter 6: Oxindole: A Nucleus Enriched with Multitargeting Potential Against Complex Disorders , Key Heterocycle Cores for Designing Multitargeting Molecules , ed. O. Silakari , Elsevier , 2018 , pp. 211–246

3. Isatin containing heterocycles for different biological activities: Analysis of structure activity relationship

4. Isatin and its derivatives: a survey of recent syntheses, reactions, and applications

5. The application of isatin-based multicomponent-reactions in the quest for new bioactive and druglike molecules

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1. The Ugi4CR as effective tool to access promising anticancer isatin-based α-acetamide carboxamide oxindole hybrids;Beilstein Journal of Organic Chemistry;2024-05-27

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