Phenyl-γ-valerolactones and phenylvaleric acids, the main colonic metabolites of flavan-3-ols: synthesis, analysis, bioavailability, and bioactivity

Author:

Mena Pedro1234ORCID,Bresciani Letizia5264ORCID,Brindani Nicoletta1234ORCID,Ludwig Iziar A.7891011ORCID,Pereira-Caro Gema12131411ORCID,Angelino Donato1234ORCID,Llorach Rafael1516171819ORCID,Calani Luca1234ORCID,Brighenti Furio1234ORCID,Clifford Michael N.2021222324ORCID,Gill Chris I. R.2526272824ORCID,Crozier Alan2930313233ORCID,Curti Claudio1234ORCID,Del Rio Daniele526434ORCID

Affiliation:

1. Department of Food & Drugs

2. University of Parma

3. 43125 Parma

4. Italy

5. Department of Veterinary Science

6. Parma

7. Functional Nutrition, Oxidation, and Cardiovascular Diseases Group (NFOC-Salut)

8. Facultat de Medicina i Ciències de la Salut

9. Universitat Rovira i Virgili

10. Reus

11. Spain

12. Department of Food Science and Health

13. IFAPA-Alameda del Obispo

14. Córdoba

15. Biomarkers & Nutrimetabolomics Laboratory

16. Department of Nutrition, Food Sciences and Gastronomy

17. XaRTA

18. INSA

19. Faculty of Pharmacy and Food Sciences

20. School of Bioscience and Medicine

21. Faculty of Health and Medical Sciences

22. University of Surrey

23. Guildford

24. UK

25. Nutrition Innovation Centre for Food and Health

26. Centre for Molecular Biosciences

27. University of Ulster

28. Coleraine

29. Department of Nutrition

30. University of California

31. Davis

32. USA

33. School of Medicine, Dentistry and Nursing

34. School of Advanced Studies on Food and Nutrition

Abstract

This review focuses on several key aspects related to the main group of phenolic metabolites in circulation.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

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