Targeting G-quadruplex structures with Zn(ii) terpyridine derivatives: a SAR study-Reference-Cited by-同舟云学术

Targeting G-quadruplex structures with Zn(ii) terpyridine derivatives: a SAR study

Published:2020 Issue:38 Volume:49 Page:13372-13385
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Busto Natalia¹²³⁴^ORCID,Carrión M. Carmen⁵⁶⁴,Montanaro Sonia⁷⁸⁹¹⁰,Díaz de Greñu Borja⁵⁶⁴^ORCID,Biver Tarita⁷⁸⁹¹⁰¹¹^ORCID,Jalón Felix A.⁵⁶⁴^ORCID,Manzano Blanca R.⁵⁶⁴^ORCID,García Begoña¹²³⁴^ORCID

Affiliation:

1. Chemistry Department

2. University of Burgos

3. 09001 Burgos

4. Spain

5. Universidad de Castilla La Mancha

6. 13071 Ciudad Real

7. Department of Chemistry and Industrial Chemistry

8. University of Pisa

9. 56124 Pisa

10. Italy

11. Department of Pharmacy

Abstract

A family of Zn(ii) terpyridine derivatives with different leaving groups and 4′-substituents was synthesized. A SAR study in terms of cytotoxicity and thermal stabilization of G-quadruplex structures is presented.

Funder

Consejería de Educación, Junta de Castilla y León

“la Caixa” Foundation

Ministerio de Ciencia, Innovación y Universidades

European Cooperation in Science and Technology

Junta de Comunidades de Castilla-La Mancha

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/DT/D0DT02125C