Cu(<scp>ii</scp>)-catalyzed ‘in-water’ <i>N</i>-arylation of electron-deficient NH-heterocycles-Reference-Cited by-同舟云学术

Cu(ii)-catalyzed ‘in-water’ N-arylation of electron-deficient NH-heterocycles

Published:2024 Issue:6 Volume:26 Page:3149-3158
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Sunny Steeva¹^ORCID,Maingle Mohit¹^ORCID,Sheeba Loddipalle¹^ORCID,Pathan Firojkhan Rajekhan¹^ORCID,J. Gowri Sankar¹,Juloori Harika¹,Gadewar Sainath Ganesh¹,Seth Kapileswar¹^ORCID

Affiliation:

1. Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER)-Guwahati, Sila Katamur, Changsari, Kamrup, 781101, Assam, India

Abstract

Cu(ii)-catalyzed robust efficient in-water N-arylation of electron-poor NH-heterocycles is reported. Wide substrate scope, decent yields, functional group tolerance, gram-scale synthesis, synthetic elaboration, late-stage arylation mirror advantages.

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/GC/D3GC05163C

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