Demonstrating the involvement of an active efflux mechanism in the intestinal absorption of chlorogenic acid and quinic acid using a Caco-2 bidirectional permeability assay-Reference-Cited by-同舟云学术

Demonstrating the involvement of an active efflux mechanism in the intestinal absorption of chlorogenic acid and quinic acid using a Caco-2 bidirectional permeability assay

Published:2021 Issue:1 Volume:12 Page:417-425
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Mortelé Olivier¹²³⁴⁵^ORCID,Jörissen Jennifer⁶⁷²⁸⁴^ORCID,Spacova Irina⁶⁷²⁸⁴,Lebeer Sarah⁶⁷²⁸⁴,van Nuijs Alexander L. N.¹²³⁴,Hermans Nina⁵²³⁴

Affiliation:

1. Toxicological Centre

2. University of Antwerp

3. 2610 Antwerp

4. Belgium

5. Natural Products and Food – Research & Analysis (NatuRA)

6. Research Group Environmental Ecology and Applied Microbiology (ENdEMIC)

7. Department of Bioscience Engineering

8. 2020 Antwerp

Abstract

The intestinal absorption of chlorogenic acid and quinic acid was investigated using an in vitro bidirectional Caco-2 permeability assay and LC-MS/MS.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/FO/D0FO02629H

Reference35 articles.

1. Recent advances in extraction and analysis procedures of natural chlorogenic acids

2. Transepithelial Transport of Chlorogenic Acid, Caffeic Acid, and Their Colonic Metabolites in Intestinal Caco-2 Cell Monolayers

3. Evaluation of the Anti-inflammatory, Analgesic and Antipyretic Activities of the Natural Polyphenol Chlorogenic Acid

4. Coffee Consumption Increases the Antioxidant Capacity of Plasma and Has No Effect on the Lipid Profile or Vascular Function in Healthy Adults in a Randomized Controlled Trial

5. Chlorogenic Acid and Rutin Play a Major Role in the In Vivo Anti-Diabetic Activity of Morus alba Leaf Extract on Type II Diabetic Rats

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