Multi-scale imaging of anticancer platinum(iv) compounds in murine tumor and kidney-Reference-Cited by-同舟云学术

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Multi-scale imaging of anticancer platinum(iv) compounds in murine tumor and kidney

Published:2016 Issue:5 Volume:7 Page:3052-3061
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Legin A. A.¹²³⁴⁵,Theiner S.¹²³⁴⁵,Schintlmeister A.⁶⁷³⁴⁵,Reipert S.⁸³⁴⁵,Heffeter P.⁹¹⁰¹¹⁴⁵,Jakupec M. A.¹²³⁴⁵,Mayr J.¹²³⁴⁵,Varbanov H. P.¹²³⁴⁵,Kowol C. R.¹²³⁴⁵,Galanski M.¹²³⁴⁵,Berger W.⁹¹⁰¹¹⁴⁵^ORCID,Wagner M.⁶⁷³⁴⁵^ORCID,Keppler B. K.¹²³⁴⁵

Affiliation:

1. Institute of Inorganic Chemistry

2. Research Platform “Translational Cancer Therapy Research,” and Research Network “Chemistry meets Microbiology”

3. University of Vienna

4. A-1090 Vienna

5. Austria

6. Department of Microbiology and Ecosystem Science

7. Research Network “Chemistry meets Microbiology”, and Large-Instrument Facility for Advanced Isotope Research

8. Core Facility of Cell Imaging and Ultrastructure Research

9. Institute of Cancer Research

10. Comprehensive Cancer Center and Research Platform “Translational Cancer Therapy Research”

11. Medical University of Vienna

Abstract

A NanoSIMS, LA-ICP-MS and TEM combinatorial approach was applied to analyze the distribution of platinum(iv) prodrugs in murine tissue samples.

Funder

European Research Council

Austrian Science Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/SC/C5SC04383B

Reference65 articles.

1. The resurgence of platinum-based cancer chemotherapy

2. NanoSIMS combined with fluorescence microscopy as a tool for subcellular imaging of isotopically labeled platinum-based anticancer drugs

3. Searching for the Magic Bullet: Anticancer Platinum Drugs Which Can Be Accumulated or Activated in the Tumor Tissue

4. What do we know about the reduction of Pt(IV) pro-drugs?

5. Kinetics and mechanism for reduction of anticancer-active tetrachloroam(m)ine platinum(IV) compounds by glutathione

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