Structure–activity relationship studies on an antitumor marine macrolide using aplyronine a–swinholide A hybrid-Reference-Cited by-同舟云学术

Structure–activity relationship studies on an antitumor marine macrolide using aplyronine a–swinholide A hybrid

Published:2022 Issue:14 Volume:20 Page:2922-2938
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Ohyoshi Takayuki¹^ORCID,Takano Atsuhiro¹,Kikuchi Imari¹,Ogura Tomotaka¹,Namiki Mayu¹,Miyazaki Yuto¹,Hirano Takahiro¹,Konishi Shota¹,Ebihara Yuta¹,Takeno Koichi¹,Hayakawa Ichiro²^ORCID,Kigoshi Hideo¹^ORCID

Affiliation:

1. Department of Chemistry, Faculty of Pure and Applied Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8571, Japan

2. Graduate School of Integrated Basic Sciences, Nihon University, 3-25-40 Sakurajosui Setagaya-Ku, Tokyo 156-8550, Japan

Abstract

Aplyronine A–swinholide A hybrid, a simplified analog of aplyronine A, was designed and synthesized for structure–activity relationship studies.

Funder

Japan Society for the Promotion of Science

Naito Foundation

Uehara Memorial Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/OB/D2OB00118G

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