Toxicity and chemical transformation of silver nanoparticles in A549 lung cells: dose-rate-dependent genotoxic impact-Reference-Cited by-同舟云学术

Toxicity and chemical transformation of silver nanoparticles in A549 lung cells: dose-rate-dependent genotoxic impact

Published:2021 Issue:3 Volume:8 Page:806-821
ISSN:2051-8153
Container-title:Environmental Science: Nano
language:en
Short-container-title:Environ. Sci.: Nano

Author:

Bobyk Laure¹²³⁴⁵,Tarantini Adeline¹²³⁴⁵,Beal David¹²³⁴⁵,Veronesi Giulia⁶¹⁷²⁸^ORCID,Kieffer Isabelle⁹¹⁰¹¹¹²¹³^ORCID,Motellier Sylvie¹¹⁴¹⁵¹²¹³^ORCID,Valsami-Jones Eugenia¹⁶¹⁷¹⁸¹⁹^ORCID,Lynch Iseult¹⁶¹⁷¹⁸¹⁹^ORCID,Jouneau Pierre-Henri¹²³⁴²⁰,Pernet-Gallay Karin¹²¹²²²²³,Aude-Garcia Catherine⁶¹⁷²⁸,Sauvaigo Sylvie²⁴²⁵²⁶¹³,Douki Thierry¹²³⁴⁵^ORCID,Rabilloud Thierry⁶¹⁷²⁸^ORCID,Carriere Marie¹²³⁴⁵^ORCID

Affiliation:

1. Univ. Grenoble Alpes

2. CEA

3. CNRS

4. IRIG

5. SyMMES

6. Chemistry and Biology of Metals

7. CNRS UMR5249

8. IRIG/DIESE/CBM

9. BM30B/FAME beamline

10. ESRF

11. Observatoire des Sciences de l'Univers de Grenoble

12. Grenoble

13. France

14. CEA/DRT/LITEN

15. Laboratoire Mesures, Sécurisation et Environnement

16. School of Geography Earth and Environmental Sciences

17. University of Birmingham

18. Birmingham B15 2TT

19. UK

20. MEM

21. Inserm, U1216

22. CHU Grenoble Alpes

23. Grenoble Institut Neurosciences

24. LXRepair

25. BIOPOLIS

26. 38700 La Tronche

Abstract

Acute exposure of A549 cells to Ag-NPs induces stronger effects on DNA integrity, ROS level, cell metabolism and cell cycle than repeated exposure. Ag-NPs dissolves in both exposure conditions and Ag ions recombine with thiolated proteins.

Funder

European Cooperation in Science and Technology

FP7 Research infrastructures

Agence Nationale de la Recherche

Seventh Framework Programme

Horizon 2020

Publisher

Royal Society of Chemistry (RSC)

Subject

General Environmental Science,Materials Science (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2021/EN/D0EN00533A