Synthesis and characterization of α,ω-end orthogonally functionalizable glycopolymers from native glycans-Reference-Cited by-同舟云学术

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Synthesis and characterization of α,ω-end orthogonally functionalizable glycopolymers from native glycans

Published:2024 Issue:18 Volume:15 Page:1884-1896
ISSN:1759-9954
Container-title:Polymer Chemistry
language:en
Short-container-title:Polym. Chem.

Author:

Keil Joseph M.¹,Chan Ka Keung¹,Sun Xue-Long¹^ORCID

Affiliation:

1. Department of Chemistry, Chemical and Biomedical Engineering and Center for Gene Regulation in Health and Disease (GRHD), Cleveland State University, 2121 Euclid Avenue, Cleveland, Ohio 44115, USA

Abstract

α,ω-End orthogonally functionalizable sialyl glycopolymers with an alkyne or azide group at one end and an O-cyanate on the other end were successfully synthesized and their orthogonal reactions via click chemistry and isourea bond formation were demonstrated.

Funder

National Institutes of Health

National Science Foundation

Cleveland State University

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/PY/D4PY00191E

Reference31 articles.

1. M. R.Thalji , A.Amin , I.Kwok and F.Chong , Glycopolymer - Based Materials: Synthesis, Properties , Springer International Publishing , 2022 , vol. 380

2. Design and synthesis of well-defined glycopolymers for the control of biological functionalities

3. End-functionalized glycopolymers as mimetics of chondroitin sulfate proteoglycans

4. Trehalose Glycopolymers for Stabilization of Protein Conjugates to Environmental Stressors

5. Synthesis of an End-to-End Protein–Glycopolymer Conjugate via Bio-Orthogonal Chemistry

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