BF3·Et2O-mediated intramolecular cyclization of unsaturated amides: convenient synthesis of dihydroquinolin-2-one-BF2 complexes

Author:

Liu Xu123,Zhang Qian123,Xin Xiaoqing123,Zhang Rui123,Zhang Ning123,Liang Yongjiu123,Dong Dewen123

Affiliation:

1. Changchun Institute of Applied Chemistry

2. Chinese Academy of Sciences

3. Changchun, China

Abstract

A facile and efficient synthesis of substituted dihydropyridone–BF2 complexes is developed via intramolecular cyclization of α-acyl acrylamides and α-acyl cinnamamides mediated by BF3·Et2O, respectively.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Reference54 articles.

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3. The 2-pyridone antibacterial agents: bacterial topoisomerase inhibitors

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5. G. Jones , Pyridines and Their Benzo Derivatives: Synthesis, in Comprehensive Heterocyclic Chemistry, ed. A. Boulton and A. McKillop, Pergamon Press, Oxford, 1984, p. 395, ch. 2.08

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